Papuamides E and F, cytotoxic depsipeptides from the marine sponge Melophlus sp.
Copyright policy ) Prasad, Pritesh; Aalbersberg, William; Feussner, Klaus-D.; Van Wagoner, Ryan M.;
Papuamides E and F, cytotoxic depsipeptides from the marine sponge Melophlus sp.
Two known papuamides C (1) and D (2) together with two new depsipeptides, papuamides E (3) and F (4), were isolated from an undescribed sponge of the genus Melophlus collected in the Solomon Islands. The planar structures of the compounds were elucidated on the basis of spectroscopic studies. Papuamides C-F (1-4) showed cytotoxicity against brine shrimp with LD(50) values between 92 and 106 μg/mL.
- University of Utah United States
- University of the South Pacific Fiji
- University of Queensland Australia
- University of Queensland Australia
1303 Biochemistry, Cytotoxic, 3002 Drug Discovery, Melophlus, Papuamide, Depsipeptide, 1605 Organic Chemistry
1303 Biochemistry, Cytotoxic, 3002 Drug Discovery, Melophlus, Papuamide, Depsipeptide, 1605 Organic Chemistry
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Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 33
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