Additional file 6: Figure S6. of Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration
Authors: AurĂŠlie Ghaye; Bergemann, David; TarifeĂąo-Saldivia, Estefania; Flasse, Lydie; Berg, Virginie Von; Peers, Bernard; Voz, Marianne; +1 Authors
AurĂŠlie Ghaye; Bergemann, David; TarifeĂąo-Saldivia, Estefania; Flasse, Lydie; Berg, Virginie Von; Peers, Bernard; Voz, Marianne; Manfroid, Isabelle;
Additional file 6: Figure S6. of Progenitor potential of nkx6.1-expressing cells throughout zebrafish life and during beta cell regeneration
Abstract
All Notch-responsive cells in the adult pancreas are CACs. Notch active cells in Tg(Tp1:VenusPest) adult fish were labeled with anti-GFP to visualize VenusPest (green) and the ductal marker 2F11 (red). VenusPest labeling is detected throughout the exocrine tissue (see asterisks highlighting examples) and where it highlights the CACs together with 2F11. In contrast, ductal structures with intense 2F11 staining do not exhibit any Venus+ (Notch on) cells. Note also the presence of 2F11 in endocrine islet cells as previously reported [79]. (PNG 2854 kb)
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