Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment
Copyright policy )Pharmacologic increase in HIF1α enhances hematopoietic stem and progenitor homing and engraftment
Key Points dmPGE2 stabilizes the transcription factor HIF1α in stem and progenitor cells. Pharmacologic stabilization of HIF1α increases CXCR4 and enhances stem and progenitor homing and engraftment.
- Indiana University United States
- Indiana University – Purdue University Indianapolis United States
- Harvard University United States
- Harvard Stem Cell Institute, Cambridge, MA, USA United States
- Indiana University School of Medicine United States
Receptors, CXCR4, Transcription, Genetic, Graft Survival, Hematopoietic Stem Cell Transplantation, alpha Subunit, Hematopoietic Stem Cells, Hypoxia-Inducible Factor 1, alpha Subunit, Dinoprostone, Hematopoietic Stem Cell Mobilization, Mice, Gene Expression Regulation, drug effects, Genetics, Animals, Hypoxia-Inducible Factor 1, pharmacology, metabolism
Receptors, CXCR4, Transcription, Genetic, Graft Survival, Hematopoietic Stem Cell Transplantation, alpha Subunit, Hematopoietic Stem Cells, Hypoxia-Inducible Factor 1, alpha Subunit, Dinoprostone, Hematopoietic Stem Cell Mobilization, Mice, Gene Expression Regulation, drug effects, Genetics, Animals, Hypoxia-Inducible Factor 1, pharmacology, metabolism
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).56 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!