Copper binding modulates the platination of human copper chaperone Atox1 by antitumor trans-platinum complexes
Copyright policy ) Zhaoyong, Xi; Wei, Guo; Changlin, Tian; Fuyi, Wang; Yangzhong, Liu;
Copper binding modulates the platination of human copper chaperone Atox1 by antitumor trans-platinum complexes
Cu(i) coordination enhances the reactivity of Atox1 towards antitumor-active trans-platinum complexes and promotes platinum transfer from the protein to dithiothreitol.
- University of Science and Technology of China China (People's Republic of)
- Chinese Academy of Sciences China (People's Republic of)
- High Magnetic Field Laboratory China (People's Republic of)
- Collaborative Innovation Center of Suzhou Nano Science and Technology China (People's Republic of)
- Moldova State University, Institute of Chemistry Moldova (Republic of)
Organoplatinum Compounds, Molecular Sequence Data, Antineoplastic Agents, Metallochaperones, Thiazoles, Copper Transport Proteins, Humans, Amino Acid Sequence, Copper, Molecular Chaperones, Protein Binding
Organoplatinum Compounds, Molecular Sequence Data, Antineoplastic Agents, Metallochaperones, Thiazoles, Copper Transport Proteins, Humans, Amino Acid Sequence, Copper, Molecular Chaperones, Protein Binding
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 12
Average
Average
Top 10%
