Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera
Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera
Key Points The novel IFNα-2b, ropeginterferon alfa-2b, administered once every 2 weeks has low toxicity and induces high and sustained response rates in polycythemia vera patients. Ropeginterferon alfa-2b induces significant partial and complete molecular response rates, as reflected by reduction of JAK2 allelic burden.
- Labor für Immunologische und Molekulare Krebsforschung Austria
- Innsbruck Medical University Austria
- Wiener Krankenanstaltenverbund Austria
- Medical University of Vienna Austria
- Austrian Academy of Sciences Austria
Adult, Aged, 80 and over, Male, Maximum Tolerated Dose, Remission Induction, Interferon-alpha, Interferon alpha-2, Middle Aged, Prognosis, Recombinant Proteins, Polyethylene Glycols, Survival Rate, Humans, Female, Polycythemia Vera, Aged, Follow-Up Studies, Half-Life, Neoplasm Staging
Adult, Aged, 80 and over, Male, Maximum Tolerated Dose, Remission Induction, Interferon-alpha, Interferon alpha-2, Middle Aged, Prognosis, Recombinant Proteins, Polyethylene Glycols, Survival Rate, Humans, Female, Polycythemia Vera, Aged, Follow-Up Studies, Half-Life, Neoplasm Staging
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