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Blood
Article
Data sources: UnpayWall
Blood
Article . 2015 . Peer-reviewed
Data sources: Crossref
Blood
Article . 2016
versions View all 2 versions

Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera

Authors: Heinz, Gisslinger; Oleh, Zagrijtschuk; Veronika, Buxhofer-Ausch; Josef, Thaler; Ernst, Schloegl; Guenther A, Gastl; Dominik, Wolf; +12 Authors

Ropeginterferon alfa-2b, a novel IFNα-2b, induces high response rates with low toxicity in patients with polycythemia vera

Abstract

Key Points The novel IFNα-2b, ropeginterferon alfa-2b, administered once every 2 weeks has low toxicity and induces high and sustained response rates in polycythemia vera patients. Ropeginterferon alfa-2b induces significant partial and complete molecular response rates, as reflected by reduction of JAK2 allelic burden.

Keywords

Adult, Aged, 80 and over, Male, Maximum Tolerated Dose, Remission Induction, Interferon-alpha, Interferon alpha-2, Middle Aged, Prognosis, Recombinant Proteins, Polyethylene Glycols, Survival Rate, Humans, Female, Polycythemia Vera, Aged, Follow-Up Studies, Half-Life, Neoplasm Staging

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    161
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 1%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
161
Top 1%
Top 10%
Top 1%
bronze