Fc RIIIb and Complement Component C7 Codeficiency in a Patient with Recurrence of Fulminant Meningococcal Septic Shock
Copyright policy )Fc RIIIb and Complement Component C7 Codeficiency in a Patient with Recurrence of Fulminant Meningococcal Septic Shock
Individuals with deficiencies of the late components of complement exhibit a susceptibility to the recurrence of meningococcal disease with a usually mild clinical presentation. We report the recurrence of fulminant meningococcal disease in a complement component C7-deficient patient. We found a total deficiency of FcgammaRIIIb on neutrophils, which could partially explain the unusually severe clinical presentation.
Adolescent, Genotype, Neutrophils, Receptors, IgG, Gene Expression, Bacteremia, GPI-Linked Proteins, Shock, Septic, Complement C7, [SDV] Life Sciences [q-bio], Meningococcal Infections, Antigens, CD, Recurrence, Humans, Female, Genetic Predisposition to Disease
Adolescent, Genotype, Neutrophils, Receptors, IgG, Gene Expression, Bacteremia, GPI-Linked Proteins, Shock, Septic, Complement C7, [SDV] Life Sciences [q-bio], Meningococcal Infections, Antigens, CD, Recurrence, Humans, Female, Genetic Predisposition to Disease
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