descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2019 English Publisher:Royal Society of Chemistry (RSC)Journal:RSC Advances, volume 9, pages 32,165-32,173 (eissn: 2046-2069,

Authors: Neil Kershaw; Dominic Byrne; Hollie Parsons; Neil G Berry; David Fernig; Patrick A. Eyers; Richard Cosstick;

doi: 10.1039/c9ra07567d , 10.26434/chemrxiv.9944243.v1

pmid: 35530783

pmc: PMC9072872

Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors

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Abstract

Regulated sulfation of biomolecules by sulfotransferases (STs) plays a role in many biological processes with implications for a number of disease areas. A structure-based approach and molecular docking were used to design a library of ST inhibitors.

Related Organizations

University of Liverpool
United Kingdom
Institute of Integrative Biology
Switzerland
University of Liverpool
Department of Biochemistry, Institute of Integrative Biology
United Kingdom

Keywords

Chemistry

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