The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility
SNSF| Investigating the in vivo roles of mammalian NDR kinases in development and colon cancer ,
SNSF| Cell Migration ,
WT| unidentified ,
SNSF| Visualizing molecular mechanisms of organ-specific T cell activation and immune surveillance ,
SNSF| Regulation of epithelial-mesenchymal transition and metastasis through phosphorylation of the transcription factor Twist by protein kinase B (PKB/Akt)
Authors: Tang Fengyuan; Gill Jason; Ficht Xenia; Barthlott Thomas; Cornils Hauke; Schmitz-Rohmer Debora; Hynx Debby; +10 Authors
Tang Fengyuan; Gill Jason; Ficht Xenia; Barthlott Thomas; Cornils Hauke; Schmitz-Rohmer Debora; Hynx Debby; Zhou Dawang; Zhang Lei; Xue Gongda; Grzmil Michal; Yang Zhongzhou; Hergovich Alexander; Hollaender Georg A; Stein Jens V; Hemmings Brian A; Matthias Patrick;
pmid: 26443704
The kinases NDR1/2 act downstream of the Hippo homolog MST1 to mediate both egress of thymocytes from the thymus and lymphocyte motility
Abstract
Signaling by kinases downstream of the Hippo homolog mediates thymocyte migration.
Related Organizations
- University of Oxford United Kingdom
- Nanjing University China (People's Republic of)
- University of Bern Switzerland
- Model Animal Research Center China (People's Republic of)
- Boston Children's Hospital United States
Keywords
Mice, Knockout, rho GTP-Binding Proteins, Thymocytes, Lymphoid Tissue, Chemotaxis, Transendothelial and Transepithelial Migration, Apoptosis, Thymus Gland, Protein Serine-Threonine Kinases, Actins, Mice, Cell Movement, T-Lymphocyte Subsets, Lymphopenia, Animals, Lymphocyte Count, Lymphocytes, Cytoskeleton
Mice, Knockout, rho GTP-Binding Proteins, Thymocytes, Lymphoid Tissue, Chemotaxis, Transendothelial and Transepithelial Migration, Apoptosis, Thymus Gland, Protein Serine-Threonine Kinases, Actins, Mice, Cell Movement, T-Lymphocyte Subsets, Lymphopenia, Animals, Lymphocyte Count, Lymphocytes, Cytoskeleton
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
66
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