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Meiosis-Specific Noncoding RNA Mediates Robust Pairing of Homologous Chromosomes in Meiosis

Authors: Da-Qiao, Ding; Kasumi, Okamasa; Miho, Yamane; Chihiro, Tsutsumi; Tokuko, Haraguchi; Masayuki, Yamamoto; Yasushi, Hiraoka;

Meiosis-Specific Noncoding RNA Mediates Robust Pairing of Homologous Chromosomes in Meiosis

Abstract

Find Your Partner Gametes generally have haploid genomes, so that when they fuse during fertilization, they reconstitute a diploid organism. Meiosis is required to make haploid gametes, which involves a reduction division where two homologous chromosomes first pair and are then segregated away from each other. Working in the fission yeast Schizosaccharomyces pombe , Ding et al. (p. 732 ; see the Perspective by Dernburg ) explored how homologous chromosomes recognized each other and found that a non-coding RNA locus, sme2 , helps to drive the pairing of homologous chromosomes.

Keywords

Recombination, Genetic, mRNA Cleavage and Polyadenylation Factors, RNA, Untranslated, Models, Genetic, Transcription, Genetic, Genes, Fungal, RNA-Binding Proteins, RNA, Fungal, Telomere, Prophase, Chromosome Pairing, Meiosis, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Chromosomes, Fungal

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
124
Top 1%
Top 10%
Top 1%