Meiosis-Specific Noncoding RNA Mediates Robust Pairing of Homologous Chromosomes in Meiosis
pmid: 22582262
Meiosis-Specific Noncoding RNA Mediates Robust Pairing of Homologous Chromosomes in Meiosis
Find Your Partner Gametes generally have haploid genomes, so that when they fuse during fertilization, they reconstitute a diploid organism. Meiosis is required to make haploid gametes, which involves a reduction division where two homologous chromosomes first pair and are then segregated away from each other. Working in the fission yeast Schizosaccharomyces pombe , Ding et al. (p. 732 ; see the Perspective by Dernburg ) explored how homologous chromosomes recognized each other and found that a non-coding RNA locus, sme2 , helps to drive the pairing of homologous chromosomes.
Recombination, Genetic, mRNA Cleavage and Polyadenylation Factors, RNA, Untranslated, Models, Genetic, Transcription, Genetic, Genes, Fungal, RNA-Binding Proteins, RNA, Fungal, Telomere, Prophase, Chromosome Pairing, Meiosis, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Chromosomes, Fungal
Recombination, Genetic, mRNA Cleavage and Polyadenylation Factors, RNA, Untranslated, Models, Genetic, Transcription, Genetic, Genes, Fungal, RNA-Binding Proteins, RNA, Fungal, Telomere, Prophase, Chromosome Pairing, Meiosis, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Chromosomes, Fungal
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