Impaired import: how huntingtin harms
Authors: Elizabeth A, Jonas;
Impaired import: how huntingtin harms
Abstract
We now learn that mutant huntingtin binds to a complex that imports constituent proteins across the mitochondrial inner membrane, halting bioenergetics in synaptic mitochondria and predisposing to neuronal dysfunction and death.
Related Organizations
- Yale University United States
Keywords
Male, Mitochondrial Proteins, Huntingtin Protein, Huntington Disease, Animals, Humans, Female, Nerve Tissue Proteins
Male, Mitochondrial Proteins, Huntingtin Protein, Huntington Disease, Animals, Humans, Female, Nerve Tissue Proteins
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citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).9 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
9
Average
Average
Average
bronze
