Alzheimer's disease risk factor complement receptor 1 is associated with depression
Copyright policy )Alzheimer's disease risk factor complement receptor 1 is associated with depression
Variation in the complement receptor 1 gene (CR1) has been identified in recent genome-wide association studies as a risk factor for Alzheimer's disease. Here, we show that two Alzheimer's disease-associated CR1 variants, rs6656401 and rs3818361, are associated with major recurrent depression in females in a population-based cohort using individuals from the Generation Scotland: Scottish Family Health Study.
- University of Glasgow United Kingdom
- University of Dundee United Kingdom
- University of Edinburgh United Kingdom
- The Queen's Medical Research Institute United Kingdom
- Glasgow Caledonian University United Kingdom
Male, Depression, 610, Alzheimer's disease, complement receptor 1 gene, Polymorphism, Single Nucleotide, Receptors, Complement, risk factor, Haplotypes, Scotland, Alzheimer Disease, depression, Humans, Female, Genetic Predisposition to Disease, Genome-Wide Association Study
Male, Depression, 610, Alzheimer's disease, complement receptor 1 gene, Polymorphism, Single Nucleotide, Receptors, Complement, risk factor, Haplotypes, Scotland, Alzheimer Disease, depression, Humans, Female, Genetic Predisposition to Disease, Genome-Wide Association Study
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