STAR, a gene family involved in signal transduction and activation of RNA
pmid: 9433137
STAR, a gene family involved in signal transduction and activation of RNA
A new subfamily of KH-domain-containing RNA-binding proteins is encoded by genes that are conserved from yeast to humans. Mutations with interesting developmental phenotypes have been identified in Caenorhabditis elegans, Drosophila and mouse. It is hypothesized that these bifunctional proteins provide a rich source of interesting molecular information about development and define a new cellular pathway that links signal transduction directly to RNA metabolism.
- The University of Texas at Austin United States
Sequence Homology, Amino Acid, Molecular Sequence Data, Nuclear Proteins, RNA-Binding Proteins, Helminth Proteins, Phosphoproteins, Mice, Mutant Strains, DNA-Binding Proteins, Mice, Mutation, Animals, Drosophila Proteins, RNA, Amino Acid Sequence, RNA Splicing Factors, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Signal Transduction, Transcription Factors
Sequence Homology, Amino Acid, Molecular Sequence Data, Nuclear Proteins, RNA-Binding Proteins, Helminth Proteins, Phosphoproteins, Mice, Mutant Strains, DNA-Binding Proteins, Mice, Mutation, Animals, Drosophila Proteins, RNA, Amino Acid Sequence, RNA Splicing Factors, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Signal Transduction, Transcription Factors
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