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Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2019Publisher:Royal Society of Chemistry (RSC)Journal:RSC Advances, volume 9, pages 21,578-21,586 (eissn: 2046-2069,

Authors: Ahmed M. Al-Abd; Hawazen A. BinMahfouz; Fahad A. Al-Abbasi; Ibrahim M. El-Deeb; Ibrahim M. El-Deeb; Hanan A. Henidi;

doi: 10.1039/c9ra03359a

pmid: 35521305

pmc: PMC9066187

Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer

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Abstract

A new series of phenylaminopyrimidine (PAP) derivatives was designed and synthesized to act against tyrosine kinases for the treatment of cancer.

Related Organizations

University of Bahrain
Bahrain
Gulf Medical University
United Arab Emirates
Griffith University
Australia
Royal College of Surgeons in Ireland
Ireland
National Research Centre
Egypt

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Chemistry

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Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer

Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer

5 Research products, page 1 of 1

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)

Εκλεκτικοί αναστολείς πρωτεϊνικών κινασών

Design, synthesis, and anticancer activity of novel 4-thiazolidinone-phenylaminopyrimidine hybrids

human src kinase bound to kinase inhibitor bosutinib

Evaluation of phenylaminopyrimidines as antifungal protein kinase inhibitors