Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

Name: Two protein-binding sites in chromatin implicated in the activation of heat-shock genes
Creator: C, Wu
Keywords: Exonucleases, 0301 basic medicine, 0303 health sciences, Deoxyribonucleases, Base Sequence, Chromatin, DNA-Binding Proteins, 03 medical and health sciences, Drosophila melanogaster, Gene Expression Regulation

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1984 English Publisher:Springer Science and Business Media LLCJournal:Nature, volume 309, pages 229-234 (issn: 0028-0836, eissn: 1476-4687,

Authors: C, Wu;

doi: 10.1038/309229a0

pmid: 6325944

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

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Abstract

The resistance to exonuclease digestion of two regions of chromatin at the 5' end of heat-shock genes in Drosophila implies they have protein bound to them. The pattern of resistance before and after induction of gene expression suggests that heat-shock genes are activated by the sequential binding of at least two protein factors.

Related Organizations

National Cancer Institute
United States
National Institute of Health
Pakistan
National Institutes of Health
United States

Keywords

Exonucleases, Deoxyribonucleases, Base Sequence, Chromatin, DNA-Binding Proteins, Drosophila melanogaster, Gene Expression Regulation, Genes, Operon, Animals, Heat-Shock Proteins

21 Research products, page 1 of 3

TATA-box-binding protein
2017IsRelatedTo
Uncharacterized protein, isoform C
2018IsRelatedTo
Heat shock protein 26
2017IsRelatedTo
Heat shock protein 68
2017IsRelatedTo
Heat shock protein 27, isoform B
2017IsRelatedTo
Heat shock protein 23, isoform B
2017IsRelatedTo
Heat shock protein 27
2017IsRelatedTo
Major heat shock 70 kDa protein Ab
2017IsRelatedTo
Heat shock protein 83, isoform B
2017IsRelatedTo
Heat shock protein 22
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