Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis
Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis
The role of pharmacogenomics, clinical and demographic parameters in pharmacokinetic predictions was evaluated in patients receiving mycophenolic acid (MPA).
- UNC Lineberger Comprehensive Cancer Center United States
- University of North Carolina at Chapel Hill United States
Adult, Male, Vasculitis, ATP Binding Cassette Transporter, Subfamily B, Polymorphism, Genetic, Genotype, Middle Aged, Mycophenolic Acid, Lupus Nephritis, Antibodies, Antineutrophil Cytoplasmic, Creatinine, UDP-Glucuronosyltransferase 1A9, Linear Models, Humans, Female, ATP Binding Cassette Transporter, Subfamily B, Member 1, Enzyme Inhibitors, Glucuronosyltransferase, Biomarkers, Aged
Adult, Male, Vasculitis, ATP Binding Cassette Transporter, Subfamily B, Polymorphism, Genetic, Genotype, Middle Aged, Mycophenolic Acid, Lupus Nephritis, Antibodies, Antineutrophil Cytoplasmic, Creatinine, UDP-Glucuronosyltransferase 1A9, Linear Models, Humans, Female, ATP Binding Cassette Transporter, Subfamily B, Member 1, Enzyme Inhibitors, Glucuronosyltransferase, Biomarkers, Aged
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