BindingDB Entry 50013694: Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.

Name: BindingDB Entry 50013694: Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.
Creator: BindingDB

Research datakeyboard_double_arrow_right Dataset 01 Jan 2022 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2kw5ktj

BindingDB Entry 50013694: Design, synthesis and biological evaluation of novel benzoxaborole derivatives as potent PDE4 inhibitors for topical treatment of atopic dermatitis.

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Abstract

Small molecule binding data for protein Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, cGMP-dependent 3',5'-cyclic phosphodiesterase, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O00408, O76074, P54750, Q01064, Q07343, Q13370, Q13946, Q14123, Q14432, and Q9Y233

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University of California, San Diego
United States

Keywords

Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C, High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, cAMP-specific 3',5'-cyclic phosphodiesterase 4B, cGMP-dependent 3',5'-cyclic phosphodiesterase, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B, and cGMP-specific 3',5'-cyclic phosphodiesterase, China Pharmaceutical University, Affinity

12 Research products, page 1 of 2

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