BindingDB Entry 50047697: Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).
doi: 10.7270/q2ks6tg9
BindingDB Entry 50047697: Discovery of a Potent, Selective, Orally Bioavailable, and Efficacious Novel 2-(Pyrazol-4-ylamino)-pyrimidine Inhibitor of the Insulin-like Growth Factor-1 Receptor (IGF-1R).
Small molecule binding data for protein 1,3-beta-glucan synthase component GLS2, CDK8/Cyclin C, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 9, Cytochrome P450 3A, Insulin-like growth factor I receptor, and MAP kinase ERK2, Uniprot P06493, P08069, P08684, P24941, P28482, P40989, P49336, P50613, and P50750
1,3-beta-glucan synthase component GLS2, CDK8/Cyclin C, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 9, Cytochrome P450 3A, Insulin-like growth factor I receptor, and MAP kinase ERK2, AstraZeneca, Affinity
1,3-beta-glucan synthase component GLS2, CDK8/Cyclin C, Cyclin-dependent kinase, Cyclin-dependent kinase 1, Cyclin-dependent kinase 2, Cyclin-dependent kinase 9, Cytochrome P450 3A, Insulin-like growth factor I receptor, and MAP kinase ERK2, AstraZeneca, Affinity
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