BindingDB Entry 50015108: Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.

Name: BindingDB Entry 50015108: Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.
Creator: BindingDB
Keywords: 3. Good health, Phosphodiesterase 1, Phosphodiesterase 3 (PDE3), Phosphodiesterase 7, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, and cGMP-specific 3',5'-cyclic phosphodiesterase, Pfizer Global Research and Development, Affinity

Research datakeyboard_double_arrow_right Dataset 01 Jan 2009 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2377855

BindingDB Entry 50015108: Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: design, synthesis and structure-activity relationship studies.

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Abstract

Small molecule binding data for protein Phosphodiesterase 1, Phosphodiesterase 3 (PDE3), Phosphodiesterase 7, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, and cGMP-specific 3',5'-cyclic phosphodiesterase, Uniprot O76074, P54750, Q01064, Q08499, Q13946, Q14123, and Q14432

Keywords

Phosphodiesterase 1, Phosphodiesterase 3 (PDE3), Phosphodiesterase 7, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, and cGMP-specific 3',5'-cyclic phosphodiesterase, Pfizer Global Research and Development, Affinity

20 Research products, page 1 of 2

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Discovery of thiadiazoles as a novel structural class of potent and selective PDE7 inhibitors. Part 1: Design, synthesis and structure–activity relationship studies
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BindingDB Entry 50015111: Spiroquinazolinones as novel, potent, and selective PDE7 inhibitors. Part 2: Optimization of 5,8-disubstituted derivatives.
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