BindingDB Entry 50045089: The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.

Name: BindingDB Entry 50045089: The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.
Creator: BindingDB
Keywords: Aurora kinase B/Inner centromere protein, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase PLK3, Serine/threonine-protein kinase PLK4, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, EntreMed Inc., Affinity, 3. Good health

Research datakeyboard_double_arrow_right Dataset 01 Jan 2016 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2125v9w

BindingDB Entry 50045089: The discovery of Polo-like kinase 4 inhibitors: design and optimization of spiro[cyclopropane-1,3'[3H]indol]-2'(1'H).ones as orally bioavailable antitumor agents.

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Abstract

Small molecule binding data for protein Aurora kinase B/Inner centromere protein, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase PLK3, Serine/threonine-protein kinase PLK4, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, Uniprot O00444, P05177, P08684, P10635, P11712, P33261, P35968, P36888, P53350, Q96GD4, Q9H4B4, and Q9NYY3

Keywords

Aurora kinase B/Inner centromere protein, Cytochrome P450 1A, Cytochrome P450 2C19, Cytochrome P450 2C9, Cytochrome P450 2D6 (2D6), Cytochrome P450 3A, Serine/threonine-protein kinase PLK1, Serine/threonine-protein kinase PLK2, Serine/threonine-protein kinase PLK3, Serine/threonine-protein kinase PLK4, Tyrosine-protein kinase receptor FLT3, and Vascular endothelial growth factor receptor 2, EntreMed Inc., Affinity

18 Research products, page 1 of 2

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