BindingDB Entry 2866: Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.

Name: BindingDB Entry 2866: Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
Creator: BindingDB
Keywords: Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Polo-Like Kinase 3, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Sunesis Pharmaceuticals, Affinity, 3. Good health

Research datakeyboard_double_arrow_right Dataset 01 Jan 2008 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q29c6vrp

BindingDB Entry 2866: Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.

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Abstract

Small molecule binding data for protein Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Polo-Like Kinase 3, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Uniprot O14965, P53350, Q05397, Q9H4B4, and Q9NYY3

Keywords

Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Polo-Like Kinase 3, Serine/threonine-protein kinase Aurora, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Sunesis Pharmaceuticals, Affinity

16 Research products, page 1 of 2

BindingDB Entry 50009916: Discovery of Novel Polo-Like Kinase 1 Polo-Box Domain Inhibitors to Induce Mitotic Arrest in Tumor Cells.
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BindingDB Entry 2829: Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.
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BindingDB Entry 50030554: Imidazopyridine derivatives as potent and selective Polo-like kinase (PLK) inhibitors.
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BindingDB Entry 50001563: Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold.
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BindingDB Entry 50047589: Small molecules that target phosphorylation dependent protein-protein interaction.
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BindingDB Entry 50045401: Identification of indole-3-carboxylic acids as non-ATP-competitive Polo-like kinase 1 (Plk1) inhibitors.
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Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors
2008IsDerivedFrom
BindingDB Entry 50001273: Design, synthesis and biological evaluation of phosphopeptides as Polo-like kinase 1 Polo-box domain inhibitors.
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BindingDB Entry 50003113: Histidine N(τ)-cyclized macrocycles as a new genre of polo-like kinase 1 polo-box domain-binding inhibitors.
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BindingDB Entry 6095: Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
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