BindingDB Entry 50033157: Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.

Name: BindingDB Entry 50033157: Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.
Creator: BindingDB
Keywords: Ephrin type-B receptor 4 (EphB4), Fibroblast growth factor receptor 1, Tyrosine-protein kinase CSK, and Vascular endothelial growth factor receptor 2, Centre de Recherches, Affinity, 3. Good health

Research datakeyboard_double_arrow_right Dataset 01 Jan 2011 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2pk0ggr

BindingDB Entry 50033157: Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.

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Abstract

Small molecule binding data for protein Ephrin type-B receptor 4 (EphB4), Fibroblast growth factor receptor 1, Tyrosine-protein kinase CSK, and Vascular endothelial growth factor receptor 2, Uniprot P11362, P35968, P41240, P54760, and Q541P7

Keywords

Ephrin type-B receptor 4 (EphB4), Fibroblast growth factor receptor 1, Tyrosine-protein kinase CSK, and Vascular endothelial growth factor receptor 2, Centre de Recherches, Affinity

7 Research products, page 1 of 1

BindingDB Entry 50045057: Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.
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BindingDB Entry 50045809: Current kinase inhibitors cover a tiny fraction of fragment space.
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BindingDB Entry 50047215: Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.
2017IsAmongTopNSimilarDocuments
Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series
2011IsDerivedFrom
BindingDB Entry 2846: Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.
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BindingDB Entry 50032427: Inhibitors of the tyrosine kinase EphB4. Part 3: identification of non-benzodioxole-based kinase inhibitors.
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BindingDB Entry 50040352: Discovery of a novel chemotype of tyrosine kinase inhibitors by fragment-based docking and molecular dynamics.
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BindingDB Entry 50033157: Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.

BindingDB Entry 50033157: Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series.

7 Research products, page 1 of 1

BindingDB Entry 50045057: Structural Analysis of the Binding of Type I, I1/2, and II Inhibitors to Eph Tyrosine Kinases.

BindingDB Entry 50045809: Current kinase inhibitors cover a tiny fraction of fragment space.

BindingDB Entry 50047215: Three stories on Eph kinase inhibitors: From in silico discovery to in vivo validation.

Inhibitors of the tyrosine kinase EphB4. Part 4: Discovery and optimization of a benzylic alcohol series

BindingDB Entry 2846: Inhibitors of the tyrosine kinase EphB4. Part 1: Structure-based design and optimization of a series of 2,4-bis-anilinopyrimidines.

BindingDB Entry 50032427: Inhibitors of the tyrosine kinase EphB4. Part 3: identification of non-benzodioxole-based kinase inhibitors.

BindingDB Entry 50040352: Discovery of a novel chemotype of tyrosine kinase inhibitors by fragment-based docking and molecular dynamics.