The Herbarium collections of the Charles University, Prague (Index Herbariorum Acronym PRC) house more than 2,300,000 specimens of algae, bryophytes, fungi, lichens, seeds / fruits, and vascular plants. Due to its size, age (founded in 1775), geographical coverage and importance (tens of thousands of type specimens), the Herbarium collections PRC belong to the biggest and most important herbaria in the world housed by university institutions. The PRC dataset contains mostly continuously sorted type specimens, recent loans (both usually with images), new accessions from students and staff of Department of Botany, Charles University, and newly acquired collections. Consequently, the majority of databased accessions represent mostly recently collected specimens (usually after 2000), though PRC also holds very old collections, besides the type material of diverse geographic provenance but mostly from Central Europe, the Balkans and Americas (e.g. type collections of G. Beck, T. Haenke).