BindingDB Entry 2829: Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.

Name: BindingDB Entry 2829: Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.
Creator: BindingDB
Keywords: Polo-Like Kinase 3, Polo-Like Kinase 4, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Abbott Laboratories, Affinity, 3. Good health

Research datakeyboard_double_arrow_right Dataset 01 Jan 2008 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q28g8j11

BindingDB Entry 2829: Pharmacological and functional comparison of the polo-like kinase family: insight into inhibitor and substrate specificity.

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Abstract

Small molecule binding data for protein Polo-Like Kinase 3, Polo-Like Kinase 4, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Uniprot O00444, P53350, Q9H4B4, and Q9NYY3

Keywords

Polo-Like Kinase 3, Polo-Like Kinase 4, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK2, Abbott Laboratories, Affinity

18 Research products, page 1 of 2

BindingDB Entry 2866: Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors.
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BindingDB Entry 6095: Substituted dihydropteridin-6-one derivatives, process for their preparation and their use as kinase inhibitors
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Pharmacological and Functional Comparison of the Polo-like Kinase Family: Insight into Inhibitor and Substrate Specificity
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BindingDB Entry 2974: Selectivity-determining residues in Plk1.
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BindingDB Entry 50001563: Design, synthesis, and biological evaluation of novel highly selective polo-like kinase 2 inhibitors based on the tetrahydropteridin chemical scaffold.
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BindingDB Entry 50047589: Small molecules that target phosphorylation dependent protein-protein interaction.
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BindingDB Entry 50045401: Identification of indole-3-carboxylic acids as non-ATP-competitive Polo-like kinase 1 (Plk1) inhibitors.
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BindingDB Entry 50043148: Design and synthesis of highly selective, orally active Polo-like kinase-2 (Plk-2) inhibitors.
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BindingDB Entry 50009455: Structure-based design and SAR development of novel selective polo-like kinase 1 inhibitors having the tetrahydropteridin scaffold.
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BindingDB Entry 2809: Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors.
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