BindingDB Entry 50009222: Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

Name: BindingDB Entry 50009222: Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.
Creator: BindingDB
Keywords: ALK tyrosine kinase receptor, Bromodomain-containing protein 4, Insulin receptor, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK3, The Institute of Cancer Research, Affinity

Research datakeyboard_double_arrow_right Dataset 01 Jan 2021 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q28s4tbz

BindingDB Entry 50009222: Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

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Abstract

Small molecule binding data for protein ALK tyrosine kinase receptor, Bromodomain-containing protein 4, Insulin receptor, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK3, Uniprot O60885, P06213, P53350, Q9H4B4, and Q9UM73

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University of California, San Diego
United States

Keywords

ALK tyrosine kinase receptor, Bromodomain-containing protein 4, Insulin receptor, Serine/threonine-protein kinase PLK1, and Serine/threonine-protein kinase PLK3, The Institute of Cancer Research, Affinity

4 Research products, page 1 of 1

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BindingDB Entry 50032006: Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like properties.
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BindingDB Entry 50009222: Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

BindingDB Entry 50009222: Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity.

4 Research products, page 1 of 1

BindingDB Entry 3114: Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding.

BindingDB Entry 3112: Discovery of thiophene inhibitors of polo-like kinase.

Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity

BindingDB Entry 50032006: Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like properties.