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Effect of Hsp70 inhibitor JG-98 on gene expression in mouse macrophages

Effect of Hsp70 inhibitor JG-98 on gene expression in mouse macrophages

Abstract

JG-98 reduces migration of macrophages. We assessed how this compound affects expression of genes associated with motility and migration. A number of motility/migration genes were significantly downregulated. Overall design: Mouse bone marrow macrophages were treated with 0.3 micromole of JG-98 for 16 hours, and RNA was isolated.

Keywords

Transcriptomics

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