IGF2/ApaIpolymorphism associated with birth weight in children of the region of Petrolina–PE, Brazil
Copyright policy )IGF2/ApaIpolymorphism associated with birth weight in children of the region of Petrolina–PE, Brazil
Insulin-like growth factor 2 (IGF2) gene has an important role in fetal growth. It was investigated association of the IGF2/ApaI polymorphism with low birth weight and normal birth weight (as control) in children attended in Hospital Dom Malan Petrolina, PE-Brazil. The genotype frequencies did not differ statistically between low birth weight (AA = 16.22%, AG = 43.24%, GG = 40.54%) and control (AA = 20% AG = 35%, GG= 45% groups) and the allele frequencies were not significantly different (p > 0.05).The observed genotype frequencies in both groups did not deviate significantly from Hardy-Weinberg equilibrium. Then, no significant correlation was found for this polymorphism in the population studied.
Geography, Infant, Newborn, Gene Frequency, Insulin-Like Growth Factor II, Pregnancy, Case-Control Studies, Birth Weight, Humans, Female, Child, Deoxyribonucleases, Type II Site-Specific, Brazil, Genetic Association Studies, Polymorphism, Restriction Fragment Length
Geography, Infant, Newborn, Gene Frequency, Insulin-Like Growth Factor II, Pregnancy, Case-Control Studies, Birth Weight, Humans, Female, Child, Deoxyribonucleases, Type II Site-Specific, Brazil, Genetic Association Studies, Polymorphism, Restriction Fragment Length
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