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ERCC1 Polymorphisms and Risk of Adult Glioma in a Chinese Population: A Hospital-Based Case-Control Study

Authors: Nu, Zhang; Lu-Yang, Lin; Lie-Lie, Zhu; Fan, Wu; Hao, Wen; Da, Pan; Yu-Chuan, Huang; +1 Authors

ERCC1 Polymorphisms and Risk of Adult Glioma in a Chinese Population: A Hospital-Based Case-Control Study

Abstract

To examine the associations of two polymorphisms in excision repair cross-complementing rodent repair deficiency complementation group 1 (ERCC1) gene, C8092A (rs3212986) and T19007C (rs11615), with the risk of adult glioma, we performed a hospital-based case-control study with 257 new cases of glioma and 278 controls in Wenzhou, China. Results showed that polymorphisms C8092A and T19007C in ERCC1 gene were not associated with the risk of glioma in a Chinese population. Further studies in Chinese populations with larger sample sizes are still warranted.

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Keywords

Adult, Male, Risk, Polymorphism, Genetic, DNA Repair, Genotype, Brain Neoplasms, Glioma, Middle Aged, Endonucleases, DNA-Binding Proteins, Asian People, Case-Control Studies, Humans, Female

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Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
20
Average
Top 10%
Top 10%