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https://doi.org/10.12681/eadd/...
Doctoral thesis . 2021 . Peer-reviewed
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ETUDE DE L'ORGANISATION ET DES PRODUITS D'EXPRESSION DU PROTO-ONCOGENE AVIAIRE C-RMIL

Authors: Calogeraki, Irene;

ETUDE DE L'ORGANISATION ET DES PRODUITS D'EXPRESSION DU PROTO-ONCOGENE AVIAIRE C-RMIL

Abstract

Le proto-oncogene aviaire c-rmil est un nouveau membre de la famille des proteines mil/raf, a activite serine/threonine kinase. Lors de passages successifs du surnageant des cellules neuroretine, infectees par le rav-1, une partie de ce gene a ete transduite par les virus ic10 et ic11. Nous demontrons ici, que les virus ic10 et ic11 sont apparus successivement au cours de la transduction. Nous presentons l'organisation de la partie codante du gene c-rmil de poule. Cette partie s'etend sur environ 100 kpb d'adn genomique et elle est constituee de 19 exons d'une taille, qui varie entre 37 et 264 pb. Nous avons mis en evidence a l'extremite 5 du gene deux exons codants, qui n'ont pas encore ete identifies chez les autres genes de cette famille. Nous avons egalement identifie un exon alternatif. Enfin, l'obtention d'un serum anti-rmil nous a permis d'identifier les proteines v-rmil dans les cellules neuroretine, ainsi qu'une proteine cellulaire de 94 kda

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
bronze