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Blood
Article
Data sources: UnpayWall
Blood
Article . 2013 . Peer-reviewed
Data sources: Crossref
Blood
Article . 2013
Data sources: Europe PubMed Central
Blood
Article
Data sources: Microsoft Academic Graph
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Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia

descriptionPublicationkeyboard_double_arrow_right Article 07 Mar 2013 English Publisher:American Society of HematologyJournal:Blood, volume 121, pages 1,783-1,794 (issn: 0006-4971, eissn: 1528-0020, Copyright policy )
Authors: Jay L. Degen; Matthew J. Flick; Xinli Du; Joseph S. Palumbo; Harini Raghu; Joni M. Prasad; Emanuel Smeds; +1 Authors

doi: 10.1182/blood-2012-09-453894

pmid: 23299312

pmc: PMC3591798

Genetic elimination of the binding motif on fibrinogen for the S. aureus virulence factor ClfA improves host survival in septicemia

Abstract

Key PointsEliminating the binding motif on fibrinogen for ClfA, but not leukocyte integrin Mac-1, improves host survival in Staphylococcus aureus septicemia.

Related Organizations
Keywords

Coagulase, Mice, Knockout, Staphylococcus aureus, Binding Sites, Virulence, Fibrinogen, Macrophage-1 Antigen, Staphylococcal Infections, Afibrinogenemia, Flow Cytometry, Bacterial Adhesion, Survival Rate, Mice, Sepsis, Animals, Cytokines

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    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 76
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
76
Top 10%
Top 10%
Top 10%
bronze
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