Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis
Authors: Flavia Sisti; Soujuan Wang; Stephanie L. Brandt; Nicole Glosson-Byers; Lindsey D. Mayo; Young Min Son; Sarah Sturgeon; +8 Authors
Flavia Sisti; Soujuan Wang; Stephanie L. Brandt; Nicole Glosson-Byers; Lindsey D. Mayo; Young Min Son; Sarah Sturgeon; Luciano Filgueiras; Sonia Jancar; Hector Wong; Charles S. Dela Cruz; Nathaniel Andrews; Jose Carlos Alves-Filho; Fernando Q. Cunha; C. Henrique Serezani;
Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis
Abstract
Nuclear localization of the phosphatase PTEN prevents cytokine storm–mediated organ injury during sepsis.
Country
United States
Related Organizations
- UNIVERSIDADE DE SAO PAULO Brazil
- Cincinnati Children's Hospital Medical Center United States
- Vanderbilt University Medical Center United States
- Universidade de São Paulo Brazil
- Indiana University – Purdue University Indianapolis United States
Keywords
Cell Nucleus, Inflammation, Male, Mice, Knockout, Gene Expression Profiling, Macrophages, PTEN Phosphohydrolase, Regulon, Mice, Inbred C57BL, MicroRNAs, Sepsis, Myeloid Differentiation Factor 88, Animals, Humans, Female, RNA Interference, Peptides
Cell Nucleus, Inflammation, Male, Mice, Knockout, Gene Expression Profiling, Macrophages, PTEN Phosphohydrolase, Regulon, Mice, Inbred C57BL, MicroRNAs, Sepsis, Myeloid Differentiation Factor 88, Animals, Humans, Female, RNA Interference, Peptides
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citations
Citations provided by BIP!
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
popularity
Popularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
19
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