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Science Signaling
Article
Data sources: UnpayWall
Science Signaling
Article . 2018 . Peer-reviewed
Data sources: Crossref
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Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis

Authors: Flavia Sisti; Soujuan Wang; Stephanie L. Brandt; Nicole Glosson-Byers; Lindsey D. Mayo; Young Min Son; Sarah Sturgeon; +8 Authors

Nuclear PTEN enhances the maturation of a microRNA regulon to limit MyD88-dependent susceptibility to sepsis

Abstract

Nuclear localization of the phosphatase PTEN prevents cytokine storm–mediated organ injury during sepsis.

Country
United States
Keywords

Cell Nucleus, Inflammation, Male, Mice, Knockout, Gene Expression Profiling, Macrophages, PTEN Phosphohydrolase, Regulon, Mice, Inbred C57BL, MicroRNAs, Sepsis, Myeloid Differentiation Factor 88, Animals, Humans, Female, RNA Interference, Peptides

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    19
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
Powered by OpenAIRE graph
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Top 10%
Top 10%
bronze