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The energy landscape of −1 ribosomal frameshifting

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 03 Jan 2020 English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 6 (eissn: 2375-2548, Copyright policy )Publicly fundedFunded by:NIH | MOLECULAR ANALYSIS OF THE..., NIH | Dynamic pathways of eukar..., SFI | Dynamic redefinition of c... +2 projects
Authors: Junhong Choi; Sinéad O’Loughlin; John F. Atkins; Joseph D. Puglisi;

doi: 10.1126/sciadv.aax6969

pmid: 31911945

pmc: PMC6938710

handle: 10147/629764

Abstract

During translation, the presence of an mRNA structure prolongs a ribosomal state favorable to spontaneous frameshifting.

Related Organizations
Keywords

GENETICS, PROTEINS, Frameshifting, Ribosomal, Open Reading Frames, Protein Biosynthesis, Escherichia coli, Nucleic Acid Conformation, RNA, Messenger, Frameshift Mutation, Ribosomes, Research Articles

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 48
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
48
Top 10%
Top 10%
Top 1%
Green
gold