The Exosome and the Proteasome: Nano-Compartments for Degradation
Copyright policy )The Exosome and the Proteasome: Nano-Compartments for Degradation
Exosomes and proteasomes are macromolecular complexes that posttranscriptionally regulate gene expression by degrading mRNAs and proteins, respectively. Although the two complexes act on different substrates and are composed of different subunits, they share a similar barrel-like architecture that appears to have evolved to restrict substrate access and prevent indiscriminate degradation.
- European Molecular Biology Laboratory Germany
- Max Planck Society Germany
- European Bioinformatics Institute United Kingdom
- Max Planck Institute of Biochemistry Germany
Proteasome Endopeptidase Complex, Protein Subunits, Binding Sites, Biochemistry, Genetics and Molecular Biology(all), Macromolecular Substances, Protein Conformation, Exoribonucleases, RNA, Substrate Specificity
Proteasome Endopeptidase Complex, Protein Subunits, Binding Sites, Biochemistry, Genetics and Molecular Biology(all), Macromolecular Substances, Protein Conformation, Exoribonucleases, RNA, Substrate Specificity
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