Pyrrole pigments in normal and congenitally anaemic mice (+/+, W/Wv, ha/ha, nb/nb, mk/mk, f/f and sla/Y)
Copyright policy )Pyrrole pigments in normal and congenitally anaemic mice (+/+, W/Wv, ha/ha, nb/nb, mk/mk, f/f and sla/Y)
Abstract 1. Values for faecal urobilinogen (UBG), serum bilirubin, and free erythrocyte protoporphyrin (FEP) are reported for normal and anaemic mice with six different hereditary anaemias. 2. Greatly increased faecal UBG and elevated serum bilirubin were found in mice with severe haemolytic anaemia (nb/nbandha/ha). 3. Mice with microcytosis (mk/mk) and sex-linked anaemia (sla/Y), both showed increased FEP and only moderate increase of faecal UBG. 4. Values for W/Wv mice fell within the normal ranges. 5. FEP levels in normal 15-day foetal red cells were extremely high. Levels for 15-day flexed anaemic foetuses (f/f) were lower, but markedly aboved adult level.
- University at Buffalo, State University of New York United States
- Jackson Laboratory United States
- State University of New York at Potsdam United States
Anemia-Hemolytic-Congenital: me, Male, Fetus: me, Erythrocytes, Porphyrins, Genotype, 610, Anemia, Hemolytic, Congenital, Anemia-Macrocytic: me, Feces, Mice, Fetus, Urobilinogen: me, Anemia-Sideroblastic: fg, Animals, Anemia, Macrocytic, Anemia, Hypochromic, me, Animal, Mice-Inbred-C57BL, Anemia, Bilirubin, 540, Anemia-Hypochromic: fg, Feces: an, Anemia, Sideroblastic, Mice, Inbred C57BL, Mutation, Urobilinogen, Erythrocytes: me
Anemia-Hemolytic-Congenital: me, Male, Fetus: me, Erythrocytes, Porphyrins, Genotype, 610, Anemia, Hemolytic, Congenital, Anemia-Macrocytic: me, Feces, Mice, Fetus, Urobilinogen: me, Anemia-Sideroblastic: fg, Animals, Anemia, Macrocytic, Anemia, Hypochromic, me, Animal, Mice-Inbred-C57BL, Anemia, Bilirubin, 540, Anemia-Hypochromic: fg, Feces: an, Anemia, Sideroblastic, Mice, Inbred C57BL, Mutation, Urobilinogen, Erythrocytes: me
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