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Quantitative T1D assessment in lipid membranes: Jeener-Broekaert NMR vs. ihMT MRI

Name: Quantitative T1D assessment in lipid membranes: Jeener-Broekaert NMR vs. ihMT MRI
Keywords: [SDV] Life Sciences [q-bio], [SPI] Engineering Sciences [physics], [PHYS] Physics [physics]

descriptionPublicationkeyboard_double_arrow_right Conference object 01 Jan 2022 France English Funded by:ANR | verISMO

Authors: Hertanu, A.; Soustelle, Lucas; de Rochefort, Ludovic; Grélard, Axelle; Dufourc, Erick J.; Alsop, David; Duhamel, Guillaume; +1 Authors

Quantitative T1D assessment in lipid membranes: Jeener-Broekaert NMR vs. ihMT MRI

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Abstract

The dipolar order relaxation time (T1D) is a probe of membrane dynamics and microstructure and could serve to further understand the relationship between the myelin membrane integrity and its biological function. In this work, the ability of quantitative inhomogeneous Magnetization Transfer (qihMT) to estimate the several T1D components of a synthetic lipid membrane system, a surrogate for the myelin membrane, was evaluated by comparison with the gold standard method for T1D quantification, the NMR Jeener-Broekaert (JB) sequence.

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France

Related Organizations

Harvard University
United States
Laboratoire Parole et Langage
France
University of Bordeaux
France
Aix-Marseille University
France
French National Centre for Scientific Research
France

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Keywords

[SDV] Life Sciences [q-bio], [SPI] Engineering Sciences [physics], [PHYS] Physics [physics]

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