Antimicrobial resistance (AMR) is a major public health concern as the proliferation of antibiotic-resistant bacteria increasingly reduces the effectiveness of our most widely used antibiotics in the treatment of bacterial diseases. The current revolution in biosciences is creating new tools that offer the chance to tackle AMR issues in the environment and create 'future-proof' technologies for new areas of application, targeting AMR issues. Successful exploitation depends on combining an enhanced understanding of the fundamental science with an ability to apply and deploy in the field for real-time monitoring to better understand the emergence and dissemination of AMR in the environment. The Anglo-Canadian Collaboration on Antimicrobial resistance (ACCAMAR) thus aims to strengthen the links between those working at the forefront of microbial genomics, metabolic capabilities, and community interactions; and those designing next-generation environmental protection technologies and human risk exposure and mitigations.