The world is moving into an unprecedented era of dam-building with more than 3700 large dams currently planned or under construction, much of which are in DAC list countries. These projects have the potential to contribute significantly to the economic and social changes that underpin global Sustainable Development Goals (SDGs). However, past experiences show that poorly designed and planned dam projects conversely may have large negative impacts on the poor, and exacerbate political instability and environmental degradation. This proposal seeks to create the knowledge base, capacity and capability for a 'Dams 2.0' future, in which dams built in DAC list countries are selected, designed and operated to support resilient and sustainable national, regional and global development in a 2.0 degC world. This will be achieved by understanding and assessing dams as interdependent human-nexus (water-energy-food-environment) system interventions and enabling stakeholders to negotiate economic, social, political and ecological impacts despite future uncertainty. Our proposal will address this ambitious goal through unique cross- and inter-disciplinary research and capacity development partnerships between three sets of key actors. First, our project will stimulate collaboration between several UK centres of research excellence in development, water-energy engineering, economics, food security, climate change, finance and ecology (the universities of Manchester (UM), Cambridge, University College London (UCL), Surrey, Newcastle and Southampton, the International Institute for Environment and Development (IIED), and the International Water Management Institute (IWMI). Second, we will consolidate links with a carefully selected network of researchers and policy-makers in 4 countries/regions (The Centre for Science and Industrial (CSIR) - Water in Ghana, Technological University of Yangon in Myanmar, Jordanian Institute of Science and Technology in the Middle East region, Institute of Economic Growth in Delhi, India). Thirdly, we will seek to work collaboratively with some of the world's most influential development organisations such as The World Bank (WB), International Union for the Conservation of Nature (IUCN), the International Finance Corporation (IFC), The Nature Conservancy (TNC), the International Hydropower Association (IHA), and the Climate Bond Initiative (CBI). Dams 2.0 is led by a team with a proven track record in successfully managing large consortium grants across multiple countries and disciplines that focus on applied development and policy impact challenges. Our work will provide tailored guidance and build capacity for water-energy-food systems management in each of our case studies regions. In addition, our project will create a framework and accompanying software toolkit for dam system design and training worldwide. This online software will link several open access water, energy, food, and ecological simulation models to state-of-the-art decision-making under uncertainty approaches. This software will be made accessible via an associated suite of online training materials (games & modules we plan to develop with IWMI and the World Bank) for use by dam selection/design/operation teams globally in a range of settings.