INDUSTRIOPHILE: tailored and robust cell-factories for next-generation Industrial Biotechnology.
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Climate change, pollution and depletion of reserves drive the search for alternatives to fossil-based resources. Micro-organisms capable of converting sustainable resources into valuable compounds (microbial cell factories, MCFs) can replace (petro)chemical products and processes, and are critical in the transition to a sustainable society. However, widespread industrial implementation of MCFs is hampered by inefficiency, instability, and complexity of current bioprocesses. Therefore INDUSTRIOPHILE develops a systematic approach to discover and improve traits in MCFs, to make them tolerant to industrial conditionals and capable of efficient production of a broad range of products. The INDUSTROPHILE approach is validated through four industrial showcases.
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