This project concerns a consortium between TU Delft (M&O group), Vrije Universiteit (KIN Group), Philips Design, and De Hartstichting for the purpose of developing smart cardiology solutions. The advent of affordable sensor and connectivity technologies can fuel developing “smart solutions” to improve the wellbeing of cardiac patients (e.g., smart devices can monitor patient behaviors and support them to change unhealthy behavior). However, most organizations struggle to initiate multi-party collaborations that are needed for developing such smart solutions. The Creative Industries are known for facilitating cross-over collaborations, but we currently lack a framework for initiating sustainable multi-party collaborations. The consortium will set up such collaborations and investigate these from a value flow and data-driven business model perspective. During workshops in the TU Delft Cardio Lab, the involved parties will integrate their knowledge by iteratively ideating and testing smart cardiology solutions. The lab will therefore become the seedbed for joint ‘design experiments’ executed by the consortium and potential other parties. This project will yield the following results: • Knowledge sharing workshops, resulting in the identification of complementarities between the parties; • Design experiments for exploring potential value flows and new business models to facilitate initiating collaborative innovation between relevant parties; • The development of a tentative framework for initiating multi-party collaborations in a designerly way; • A grant proposal for further developing and testing the tentative framework. We will disseminate these results to a broader community of healthcare and creative professionals through practitioner- and researcher-oriented workshops.