The identification and functional analysis of translationally regulated mRNAs important for stem cell identity
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Stem cells are vital for our health. In the intestine, they maintain the organ, and allow it to heal after damage. Changes in these cells in the intestine are known to cause diseases including cancer and ulcerative colitis. In this proposal we will study these cells in order to understand how they make the proteins they need, and how this process is hijacked by disease. In doing this we can potentially identify ways to modify this, improving the health of the organ.
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