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The human body contains more microorganisms than its own cells and may contain more microbial genes than there are stars in observable universe. Thus, these greatly influence human physiology, both in health and disease. Despite their abundance in semen we barely know anything about their influence on fertility of men, the health of the couple, miscarriage rates and even the health of offspring. In the project genetic techniques and nanoscale magnetic resonance imaging (nano-MRI) will be used to unravel which microorganisms are in semen, how they influence sperm cells and the consequences this has for the fertility of men.
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