Sense, Decide, Develop: how to maintain accuracy in gene regulation and development
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For organisms to develop well, cell-fate decisions need to be made correctly, and these in turn are based on an accurate sense of the cell’s environment. Researchers will investigate mechanistic processes which contribute to noise, regarding the spatial structure of the genome, on the one hand, and develop information-theoretical and mathematic frameworks to infer optimal network architectures from experimental data on the other. This project is based on experimental collaborations in a series of developing systems, from flies to viruses.
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