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Back in fear: investigating the synaptic signatures of fear extinction and relapse in the memory engram

Funder: Netherlands Organisation for Scientific Research (NWO)Project code: VI.Veni.212.064

Back in fear: investigating the synaptic signatures of fear extinction and relapse in the memory engram

Description

Memories are stored in the brain as changes in the connectivity between neurons. This project will develop a new technology to capture the neuronal connectivity footprints of specific memories in the brain and investigate the exact mechanisms by which fear memories are stored, erased and may relapse over time. Herinneringen zijn in het brein opgeslagen als veranderingen in verbindingen tussen hersencellen. Dit project zal een nieuwe techniek ontwikkelen waarmee we deze verbindingen kunnen meten en onderzoeken hoe specifieke angstherinneringen worden opgeslagen, tijdelijk uitdoven maar ook kunnen terugkeren met het verstrijken van tijd.

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