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Lighting the Way of Drug Discovery: Photochemical Synthesis of Non-Natural Amino Acids

Funder: Netherlands Organisation for Scientific Research (NWO)Project code: VI.Veni.222.279
Funded under: NWO-Talentprogramma Veni ENW 2022

Lighting the Way of Drug Discovery: Photochemical Synthesis of Non-Natural Amino Acids

Description

The photochemical synthesis of non-natural amino acids is a promising approach for drug discovery. This method utilizes visible light to create new amino acids that can be incorporated into proteins or small molecules to create new drug candidates with improved properties such as increased stability or specificity. Mild photochemical synthesis of non-natural amino acids also allows for the precise control of their chemical structure, which can lead to more selective and effective drug candidates. In this project new non-natural amino acids will be made with blue light photocatalysis to ensure a supply of these powerful building blocks for future medicines.

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