Recent years have seen a growing number of studies on the genetic basis of risk behaviors, such as smoking, alcohol and drug use, and delinquency, showing cumulative evidence that genetic disposition helps explaining individual variation in engagement in risk behaviors, particularly in interplay with the (social) environment. In adolescence, the peer environment constitutes one of the most important contexts for social and emotional development, especially with regard to risk behaviors (Bukowski et al., 2006). Strikingly, there is little genetically informed research on adolescents? development in the peer context. Only a handful of studies have examined the gene-environment interplay in relation to the peer context, using a candidate genes approach. Whereas these studies provide valuable results into how genetic dispositions may affect adolescents? behaviors in relation to peer behaviors and experiences, they suffer from important weaknesses. Most prominently, they rely on adolescents? self-reports of their friends? behaviors, which are subject to a false consensus bias. Moreover, many studies are limited to cross-sectional associations between the behaviors of peers and adolescents, which does not reveal whether similarity emerges from the selection of similar peers (i.e., selection processes) or adaptation of peers? behaviors (i.e., influence processes). Methodological advancements in longitudinal social network analysis enable a more precise and objective assessment of these processes. This approach has proven superior in capturing the complexity and richness of the peer context, yielding a rapidly growing number of studies on selection and influence processes regarding risk behaviors. Although research on genetic antecedents of behavior and social network modeling have independently proven their merits in elucidating why adolescents engage in risk behaviors, data on genetic factors in combination with longitudinal social network information is to date lacking entirely. The aim of this investment is to bridge both promising lines of research by obtaining genotypic information within SNARE (Social Network Analysis of Risk behavior in Early adolescence), an ongoing study on the development of adolescents? risk behavior including longitudinal information about adolescents? social networks. SNARE is conducted among first and second year students of the by far largest school for secondary education in a region in the northern part of the Netherlands with four different locations, covering all academic tracks (N = 1,100) (97% participation rate). Targeting all students in this school resulted in the inclusion of the largest possible number of respondents and their potential peers between 12 and 16 years. The sample is ethnically homogenous (96% Caucasian), which makes it very well-suited for examining genetic effects. Integrating genetic research with longitudinal social network modeling yields an internationally unique opportunity to examine to what extent genetic dispositions interplay with the peer context in explaining the development and social consequences of adolescents? risk behaviors, putting this dataset at the forefront of research on adolescents? development in the fields of behavioral genetics, developmental psychology, criminology, education, and sociology.