<< Background >>The European project ATHIKA (Advanced Training in Health Innovation Knowledge Alliance) was born with the purpose of bringing a humanistic approach to the engineering education while addressing the most important new research in the world of AI and IoT linked to Healthcare. It has been achieved by building a set of advanced training programs for students, involving academia, health public administration, SMEs, startups and entrepreneurs, and health business consultants.<< Objectives >>ATHIKA project has successfully achieved the objectives by developing a KA through the cooperation and involvement of the HEIs, SMEs and Industry of the KA with the final result of an international multidisciplinary free-access online eHealth course for all backgrounds that provides the tools (key digital competences, job-specific skills, ethical awareness, innovative pedagogies, cutting-edge knowledge, Challenge Based Learning) to face eHealth challenges(from technical and business perspective)<< Implementation >>The ATHIKA project designed the ATHIKA Framework for the eHealth Challenge identification and Scenario Planning, the companies designed their challenges using it. In parallel, the HEIs prepared the ATHIKA course platform, focusing on a common part (eHealth sector and Fundamentals) and on a specific part for IoT, AI&Ml and Gov&ethics has been developed. After deploying the course, a workshop, competition and mobility was hosted. A refinement has been applied following the students' feedback.<< Results >>- ATHIKA framework (Health and Smart City Ecosystem Framework)- ATHIKA course (Unit 1-eHealth; Unit 2-Fundamentals; Unit 3-IoT; Unit3-AI Unit3-Governance&Ethics). More than >180 international students involved- ATHIKA IoT Lite (>300 undergraduate students involved)- ATHIKA competitions (>70 students participated; 12 students won)- ATHIKA Mobility (9 students travelled to the companies of the project)