"Below presented project – Simulation in Undergraduate MEDical Education for Improvement of SAFEty and Quality of Patient Care (SAFEMED+) serves to tackle important issues, related to undergraduate medical education in Georgia, Armenia and Ukraine, which takes roots back from collapse of Soviet Union and crush of soviet educational system. Despite progressive steps, taken by partner countries towards adopting wester values and implementing up-to-date trends within educational systems as well, undergraduate medical education and practical training of prospective medical professionals particularly, yet remains to be a weak link on the regional level. Taking into consideration national and regional priorities, as well as common needs, was born an idea to develop a project, which would address existing common challenges, yet provide bespoke solutions for given concerns of participating institutions. The project SAFEMED+ was first introduced during KA-2 CBHE call 2016-2017, under name SAFEMED and with rather different formation of consortia, which was shortlisted and placed among reserve projects with best positive feedbacks and valuable recommendations for further improvement. Addition of ""+"" in acronym indicates addition of simulations to the essential body of the project, implying development of all necessary types of simulations, which may be used on the undergraduate stage of medical education, including standardized patients, mannequin-equipped clinical skills laboratory, clinical scenarios, OSCE examinations etc; in order to create a continuum of clinical competences across the curriculum, starting from the first year of studies in Competency Based Medical Education based Curriculum.The enhancement of patient care safety and quality by promoting simulated learning of Clinical Skills implemented in Competency Based Medical Education based Curriculum in Undergraduate Students is the primary impact of the SAFEMED+."