ENZYCLE’ overall objective is to valorise and upgrading non-recycled plastic fractions through enzymatic processes to obtain high value-added products. For this, enzymes with a high hydrolytic activity on polyesters (PET) and on polyolefins (PE and PP) will be identified and selected in order to establish an efficient production process and developing recycling processes on plastic fractions that are currently not recycled. Additionally, ENZYCLE will deal with the problem with microplastics and their high environmental and health impact. Within ENZYCLE project, new processes for enzymatic recycling of multilayer packaging, post-consumer PET trays and clamshell and microplastics will be developed with the aim of enhancing the sustainability of these wastes, within a framework of circular economy, so as to save material and economic resources, creating new value chains by turning them into valuable products and closing the loop value chain by introducing the final obtained products back in the production process for plastic polymers.