With the evolving threat of climate change and the consequences of industrial accidents to becoming more severe, there is an increasing need for First Responders to access reliable and agile information management systems that offer as higher Situational Awareness and better Common Operational Picture. To match with current trends, the RESPOND-A project aims at developing holistic and easy-to-use solutions for First Responders by bringing together the complementary strengths of its Investigators in 5G wireless communications, Augmented and Virtual Reality, autonomous robot and unmanned aerial vehicle coordination, intelligent wearable sensors and smart monitoring, geovisual analytics and immersive geospatial data analysis, passive and active localisation and tracking, and interactive multi-view 360o video streaming. The synergy of such cutting-edge technological advancements is likely to provide high-end and continuous flows of data, voice and video information to First Responders and their Command & Control Centres for predicting and assessing the various incidents readily and reliably, and saving lives more efficiently and effectively, while maximising the safeguarding of themselves, before, during and after disasters. To this end, RESPOND-A envisions at exercising First Responders for getting familiar with the project technological outcomes, and demonstrating their real-world performance and effectiveness in the classified training facilities of our Responder Partners under hydrometeorological, geophysical and technological disaster scenarios.