QLSI2 brings together the expertise of 23 partners from 9 countries with the ambition to demonstrate a cloud-accessible 200-qubit semiconductor-based quantum computer by the end of 2027. In addition, the consortium aims to demonstrate the implementation of meaningful use cases on this demonstrator. The QLSI2 project will leverage the expertise of key European players (RTOs, academic laboratories, start-ups and large companies) in complementary fields of quantum technologies, from hardware to software, to define and implement a roadmap towards such an ambitious goal. The roadmap will extend its vision to the entire value chain, including the supply chain. Particular attention will be paid to the industrialisability of the proposed solution in order to keep Europe at the forefront of the race for quantum supremacy for a long time to come. The roadmap will be implemented considering both heterostructure-based and FD-SOI-based routes. In addition, and following these two routes, QLSI2 aims to advance both technology and manufacturing readiness to a level high enough to meet Europe's ambitions for the industrialisation of quantum technologies, with a particular focus on scalability. With these overall objectives and expected outcomes, QLSI2 will have a significant impact on the field towards LSQ.