LaserCell envisions an innovative approach to reshape and rearrange cellulose at the molecular level by disrupting cohesive interactions through resonant excitation of specific bonds. It will revolutionize the field of biopolymer processing beyond cellulose and yield fundamental insights into supramolecular structure and dynamics in biomaterials. Although cellulose is biodegradable and mechanically strong, it cannot be processed by conventional thermoplastic polymer methods, which limits its use as high-volume material. Cellulose decomposes before it melts because of cooperative intermolecular hydrogen bonding and hydrophobic interactions. To plasticise cellulose, I propose to disrupt these intermolecular bonds with photon energy delivered by infrared (IR) laser pulses. Employing wavelengths matching specific vibrational modes, the photon energy will be resonantly absorbed, thus effectively plasticising cellulose. I envision that the rapid energy dissipation in short pulses will deliver enough peak power to disrupt the intermolecular bonds yet avoiding thermal damage. I plan to systematically investigate how laser parameters influence the supramolecular structure of cellulose and establish analytical tools to characterize its structural transitions under mechanical load. Additionally, to allow processability in different set-ups, I aim to prolong the time window of plasticization and adjust the flowability, by using the laser irradiation in synergy with the hydrogen disrupting molecules. As a proof of concept, I will implement this novel photo-plasticization technique into a cellulose fibre spinning process and post-treatment to modulate the cellulose fibre crystallinity. I have worked for 10 years on cellulose-based materials and have a strong background in fibre spinning and material science. My research group will engage 1 PhD student and 2 Postdocs with background in polymer science and laser physics and technology.